Open AccessEvaluation of Collagen Gel-Associated Human Nasal Septum-Derived Chondrocytes As a Clinically Applicable Injectable Therapeutic Agent for Cartilage Repair
Author(s) -
Mi Hyun Lim,
Jung Ho Jeun,
Do Hyun Kim,
Sun Hwa Park,
Seok Jung Kim,
Weon Sun Lee,
Se Hwan Hwang,
Jung Yeon Lim,
Sung Won Kim
Publication year - 2020
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00261-9
Subject(s) - cartilage , regeneration (biology) , chondrocyte , nasal septum , chemistry , chondrogenesis , tissue engineering , pathology , medicine , microbiology and biotechnology , biomedical engineering , surgery , anatomy , biology , nose
Articular cartilage injury has a poor repair ability and limited regeneration capacity with therapy based on articular chondrocytes (ACs) implantation. Here, we validated the hypothesis that human nasal septum-derived chondrocytes (hNCs) are potent therapeutic agents for clinical use in cartilage tissue engineering using an injectable hydrogel, type I collagen (COL1).