Open AccessChemical Regeneration of Wound Defects: Relevance to the Canine Palatal Mucosa and Cell Cycle Up-Regulation in Human Gingival Fibroblasts
Author(s) -
Kyung-Ho Lee,
Heithem Ben Amara,
Sang Cheon Lee,
Richard Liu,
Min Ah Chung,
KiTae Koo,
Suk Won Lee
Publication year - 2019
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-019-00227-6
Subject(s) - wound healing , regeneration (biology) , cell cycle , oral mucosa , cell growth , biology , microbiology and biotechnology , cell , immunology , biochemistry , anatomy
Trichloroacetic acid (TCA) is an agent widely applied in dermatology for skin regeneration. To test whether TCA can offer an advantage for the regeneration of oral soft tissue defects, the cellular events following TCA application were explored in vitro and its influence on the oral soft tissue wound healing was evaluated in a canine palate model.