Open AccessAn Important Role of Macrophages for Wound Margin Regeneration in a Murine Flap Model
Author(s) -
Ho-Ryun Won,
Chorong Seo,
Hyeyoung Lee,
Jin Roh,
ChulHo Kim,
Jeon Yeob Jang,
Yoo Seob Shin
Publication year - 2019
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-019-00214-x
Subject(s) - wound healing , hacat , regeneration (biology) , macrophage , infiltration (hvac) , keratinocyte , inflammation , pathology , cell migration , cell culture , microbiology and biotechnology , medicine , chemistry , immunology , biology , in vitro , biochemistry , genetics , physics , thermodynamics
Macrophages have been known to have diverse roles either after tissue damage or during the wound healing process; however, their roles in flap wound healing are poorly understood. In this study, we aimed to evaluate how macrophages contribute to the flap wound regeneration.