Open AccessSpreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells
Author(s) -
Yang Zhao,
Qing Sun,
Shurong Wang,
Bo Huo
Publication year - 2019
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-019-00213-y
Subject(s) - mesenchymal stem cell , cytochalasin d , microbiology and biotechnology , cellular differentiation , cell , actin , chemistry , stem cell , biology , cytoskeleton , biochemistry , gene
Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies focused on the effect of the circularity of cell shape on the osteogenic differentiation of MSCs with a confined area during osteogenic process.