Open AccessNear-Infrared Contrast Agents for Bone-Targeted Imaging
Author(s) -
Joohee Jung,
Daewoong Jo,
Gayoung Jo,
Hoon Hyun
Publication year - 2019
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-019-00208-9
Subject(s) - bone tissue , contrast (vision) , biomedical engineering , chemistry , medicine , computer science , artificial intelligence
For the bone-specific imaging, a structure-inherent targeting of bone tissue recently has been reported a new strategy based on incorporation of targeting moieties into the chemical structure of near-infrared (NIR) contrast agents, while conventional methods require covalent conjugation of bone-targeting ligands to NIR contrast agents. This will be a new approach for bone-targeted imaging by using the bifunctional NIR contrast agents.