Open AccessUltrasound Based Computational Fluid Dynamics Assessment of Brachial Artery Wall Shear Stress in Preeclamptic Pregnancy
Author(s) -
Ryan Pewowaruk,
Jenna L. Racine,
J. Igor Iruretagoyena,
Alejandro RoldánAlzate
Publication year - 2020
Publication title -
cardiovascular engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 25
eISSN - 1869-4098
pISSN - 1869-408X
DOI - 10.1007/s13239-020-00488-6
Subject(s) - brachial artery , ultrasound , shear stress , pregnancy , dynamics (music) , medicine , cardiology , obstetrics , materials science , radiology , composite material , acoustics , blood pressure , biology , physics , genetics
Preeclampsia (PE) is a pregnancy complication of abnormally elevated blood pressure and organ damage where endothelial function is impaired. Wall shear stress (WSS) strongly effects endothelial cell morphology and function but in PE the WSS values are unknown. WSS calculations from ultrasound inaccurately assume cylindrical arteries and patient specific computational fluid dynamics (CFD) typically require time-consuming 3D imaging such as CT or MRI.