Open AccessSolitary Pancreatic Head Metastasis from Ductal Carcinoma of Breast: A Case Report
Author(s) -
Parag Ingle,
Pravin Ashok Khandare,
Manjit Rajput,
Manish Tiwari,
Mangesh Patil,
Ajay Mehta
Publication year - 2021
Publication title -
indian journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 16
eISSN - 0976-6952
pISSN - 0975-7651
DOI - 10.1007/s13193-021-01284-x
Subject(s) - medicine , breast cancer , metastasis , surgical oncology , pancreatic cancer , exemestane , cytokeratin , radiology , adenocarcinoma , radiation therapy , oncology , pathology , cancer , tamoxifen , immunohistochemistry
Liver, bones, and brain are common sites for breast cancer metastasis. We report here a rare scenario of metastasis to pancreatic head from breast cancer after a disease free interval of 7 years. A 60-year old breast cancer survivor noticed upper abdominal pain for 2 weeks, and her investigations revealed a pancreatic head mass lesion. Computed tomography imaging revealed a solitary pancreatic mass lesion with portal cavernoma formation and a guided biopsy yielded adenocarcinoma on histopathological examination. Immunohistochemistry processing demonstrated estrogen receptor, cytokeratin 7, and GATA 3 positivity which confirmed it to be a metastasis. Therapy was initiated with palbociclib and exemestane. Later, everolimus was started in view of failure of hormonal therapy. The patient is still alive 21 months after diagnosing the recurrence.