
Cardiac Collapse Secondary to Phenytoin Toxicity in a Neonate Treated with Extracorporeal Membrane Oxygenation Support (ECMO)
Author(s) -
Michelle Knecht,
Joseph M. LaRochelle,
Brian Barkemeyer,
Raegan W. Gupta,
Michael R. Brumund,
Christy Mumphrey
Publication year - 2019
Publication title -
journal of medical toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.534
H-Index - 49
eISSN - 1937-6995
pISSN - 1556-9039
DOI - 10.1007/s13181-019-00742-x
Subject(s) - medicine , phenytoin , extracorporeal membrane oxygenation , toxicity , anesthesia , pharmacology , epilepsy , psychiatry
Although medication toxicity is uncommon in neonates, there are several medications used in this population that pose a risk. Phenytoin has an increased risk of toxicity given its narrow therapeutic window and variations in drug elimination.