Open AccessQuantification of Hypoxia in Human Glioblastoma using PET with 18F-FMISO
Author(s) -
Redha-alla Abdo,
F. Lamare,
Philippe Fernandez,
M’hamed Bentourkia
Publication year - 2021
Publication title -
nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.534
H-Index - 23
eISSN - 1869-3482
pISSN - 1869-3474
DOI - 10.1007/s13139-021-00693-8
Subject(s) - voxel , nuclear medicine , medicine , glioblastoma , pet imaging , tumor hypoxia , hypoxia (environmental) , positron emission tomography , oxygen , radiology , radiation therapy , chemistry , organic chemistry , cancer research
This study aimed to investigate the results of compartmental modeling (CM) and spectral analysis (SA) generated with dynamic 18F-FMISO tumor images. Besides, the regular tissue-to-blood ratio (TBR) images were derived and compared with the dynamic models.