Open AccessThe effect of a low-nickel diet and nickel sensitization on gastroesophageal reflux disease: A pilot study
Author(s) -
Ahmed Yousaf,
Rachael Hagen,
Mary Mitchell,
Erica Ghareeb,
Wei Fang,
Raoul Correa,
Zachary Zinn,
Swapna Gayam
Publication year - 2020
Publication title -
indian journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.558
H-Index - 41
eISSN - 0975-0711
pISSN - 0254-8860
DOI - 10.1007/s12664-020-01090-3
Subject(s) - gerd , medicine , gastroenterology , reflux , disease
Gastroesophageal reflux disease (GERD) is a common medical condition, frequently refractory to medical therapy. Nickel is a leading cause of allergic contact dermatitis. Although nickel is widely found in foods, the effect of nickel on GERD is unknown. This pilot study sought to evaluate the effect of a low-nickel diet on GERD and determine if epicutaneous patch testing to nickel could predict responsiveness to a low-nickel diet.