Open AccessComparative Evaluation of IV Paracetamol Versus IV Dexmedetomidine in Inpatient Oral and Maxillofacial Surgery: A Double-Blinded Randomized Controlled Study
Author(s) -
Khurshid Guru,
S Adinarayanan,
Balasubramanian Krishnan,
Satyen Parida,
Hemavathi Balachander,
Prasanna Udupi Bidkar,
K Narmadhalakshmi
Publication year - 2019
Publication title -
journal of maxillofacial and oral surgery/journal of maxillofacial and oral surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.293
H-Index - 21
eISSN - 0974-942X
pISSN - 0972-8279
DOI - 10.1007/s12663-019-01264-3
Subject(s) - medicine , dexmedetomidine , analgesic , anesthesia , visual analogue scale , oral and maxillofacial surgery , sedation , sedative , surgery , adverse effect , reconstructive surgery
Reconstructive surgeries following fractures in the maxillofacial region often involve considerable bone manipulation, and paracetamol is a commonly used analgesic medication in both intraoperative and postoperative periods. Dexmedetomidine, an alpha-2 adrenoceptor agonist, has both sedative and analgesic properties with minimal cardiorespiratory effects and has been used primarily for its sedative properties in oral and maxillofacial surgery.