Open AccessNormal delivery following resection of an androgen‐secreting adrenal carcinoma
Author(s) -
Amano Toshiyasu,
Imao Tetsuya,
Seki Masaya,
Takemae Katsurou,
Yamauchi Keishi,
Hata Satoru
Publication year - 2011
Publication title -
reproductive medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.005
H-Index - 22
eISSN - 1447-0578
pISSN - 1445-5781
DOI - 10.1007/s12522-010-0071-4
Subject(s) - medicine , adrenocortical carcinoma , adrenalectomy , testosterone (patch) , amenorrhea , pathological , androgen , carcinoma , menstruation , gynecology , urology , hormone , pregnancy , genetics , biology
A 31‐year‐old female presented to a gynecological clinic complaining of amenorrhea and virilism over a 2‐month period. Blood tests revealed high serum total testosterone and free testosterone levels. A left adrenal tumor was identified following computed tomography and she was referred to our clinic where a laparoscopic left adrenalectomy was performed. The tumor weighed 98 g and the pathological diagnosis according to Weiss’ criteria was adrenocortical carcinoma. The post‐operative course was uneventful; her serum free testosterone level normalized and regular menstruation was observed 1 month post‐operatively. The patient became pregnant 1 year later, resulting in the normal delivery of a girl.