Open AccessEvaluation of possible criteria for elective single embryo transfer
Author(s) -
Sato Wataru,
Fukuda Jun,
Kanamori Kyoko,
Kawamura Kazuhiro,
Kumagai Jin,
Kodama Hideya,
Tanaka Toshinobu
Publication year - 2010
Publication title -
reproductive medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.005
H-Index - 22
eISSN - 1447-0578
pISSN - 1445-5781
DOI - 10.1007/s12522-010-0047-4
Subject(s) - medicine , gestation , single embryo transfer , pregnancy , obstetrics , reproductive medicine , logistic regression , pregnancy rate , gynecology , genetics , biology
Abstract Purpose A major problem of assisted reproductive technology (ART) is multiple gestation, which impacts neonatal and perinatal medicine. The literature contains a number of reports that elective single embryo transfer (eSET) is effective for the control of multiple pregnancies; however, to date, uniform criteria have not been established. Methods Using logistic regression analysis based on the results of ART in our department from January 2005 to July 2006, our eSET criteria were established. We conducted a comparative study of the clinical pregnancy rate, multiple gestation rate, and delivery rate before and after eSET (before‐eSET and after‐eSET groups, respectively). Results As a result of the analysis, our eSET criteria included all three of the following: (A) patient age ≤37, (B) previous IVF/ICSI trials ≤5, and (C) acquisition of two or more good‐quality embryos. Based on our criteria, the after‐eSET group was not found to have a decrease in the pregnancy rate; however, the multiple gestation rate decreased as compared to the before‐eSET group. In addition, as a result of various evaluations of the eSET group, interesting findings were revealed. Conclusions In the after‐eSET group, our eSET criteria achieved a decrease in the multiple pregnancy rate without a decrease in the pregnancy rate.