Open AccessSimultaneous determination of dynamic cardiac metabolism and function using PET/MRI
Author(s) -
Gregory P. Barton,
Lauren Vildberg,
Kara N. Goss,
Niti R. Aggarwal,
Marlowe W. Eldridge,
A. McMillan
Publication year - 2019
Publication title -
journal of nuclear cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 82
eISSN - 1532-6551
pISSN - 1071-3581
DOI - 10.1007/s12350-018-1287-7
Subject(s) - medicine , ejection fraction , cardiac function curve , positron emission tomography , cardiac pet , cardiology , magnetic resonance imaging , fluorodeoxyglucose , cardiac imaging , cardiac magnetic resonance imaging , nuclear medicine , hypoxia (environmental) , heart failure , radiology , oxygen , chemistry , organic chemistry
Cardiac metabolic changes in heart disease precede overt contractile dysfunction. However, metabolism and function are not typically assessed together in clinical practice. The purpose of this study was to develop a cardiac positron emission tomography/magnetic resonance (PET/MR) stress test to assess the dynamic relationship between contractile function and metabolism in a preclinical model.