Open AccessHybrid solid-state SPECT/CT left atrial innervation imaging for identification of left atrial ganglionated plexi: Technique and validation in patients with atrial fibrillation
Author(s) -
James Stirrup,
Sima Gregg,
R Baavour,
Nathaniel Roth,
Christopher Breault,
Arnaud Denis,
Sabine Ernst,
S. Richard Underwood
Publication year - 2020
Publication title -
journal of nuclear cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 82
eISSN - 1532-6551
pISSN - 1071-3581
DOI - 10.1007/s12350-018-01535-5
Subject(s) - medicine , atrial fibrillation , cardiology , pulmonary vein , gating , nuclear medicine , confidence interval , physiology
Ablating left atrial (LA) ganglionated plexi (GP), identified invasively by high-frequency stimulation (HFS) during pulmonary vein isolation (PVI), may reduce atrial fibrillation (AF) recurrence. 123 I-metaiodobenzylguanidine ( 123 I-mIBG) solid-state SPECT LA innervation imaging (LAII) has the spatial resolution to detect LAGP non-invasively but this has never been demonstrated in clinical practice.