Hybrid solid-state SPECT/CT left atrial innervation imaging for identification of left atrial ganglionated plexi: Technique and validation in patients with atrial fibrillation | Zendy

James Stirrup | Zendy; Sima Gregg | Zendy; Raphael Baavour | Zendy; N. Roth | Zendy; Christopher Breault | Zendy; D. Agostini | Zendy; Sabine Ernst | Zendy; S. Richard Underwood | Zendy

Open Access

Hybrid solid-state SPECT/CT left atrial innervation imaging for identification of left atrial ganglionated plexi: Technique and validation in patients with atrial fibrillation

Author(s) -

James Stirrup,

Sima Gregg,

Raphael Baavour,

N. Roth,

Christopher Breault,

D. Agostini,

Sabine Ernst,

S. Richard Underwood

Publication year - 2019

Publication title -

journal of nuclear cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.791

H-Index - 82

eISSN - 1532-6551

pISSN - 1071-3581

DOI - 10.1007/s12350-018-01535-5

Subject(s) - medicine , atrial fibrillation , cardiology , pulmonary vein , gating , nuclear medicine , confidence interval , physiology

Ablating left atrial (LA) ganglionated plexi (GP), identified invasively by high-frequency stimulation (HFS) during pulmonary vein isolation (PVI), may reduce atrial fibrillation (AF) recurrence. 123 I-metaiodobenzylguanidine ( 123 I-mIBG) solid-state SPECT LA innervation imaging (LAII) has the spatial resolution to detect LAGP non-invasively but this has never been demonstrated in clinical practice.

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