Open AccessWhat signals the glyoxalase pathway in plants?
Author(s) -
Sampurna Garai,
Bidisha Bhowal,
Charanpreet Kaur,
Sneh L. SinglaPareek,
Sudhir K. Sopory
Publication year - 2021
Publication title -
physiology and molecular biology of plants/physiology and molecular biology of plants
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 35
eISSN - 0971-5894
pISSN - 0974-0430
DOI - 10.1007/s12298-021-00991-7
Subject(s) - methylglyoxal , crosstalk , abiotic component , biology , metabolic pathway , signal transduction , biochemistry , microbiology and biotechnology , lactoylglutathione lyase , organism , abiotic stress , enzyme , detoxification (alternative medicine) , plant physiology , endogeny , chemistry , botany , ecology , genetics , gene , medicine , physics , alternative medicine , pathology , optics
Glyoxalase (GLY) system, comprising of GLYI and GLYII enzymes, has emerged as one of the primary methylglyoxal (MG) detoxification pathways with an indispensable role during abiotic and biotic stresses. MG homeostasis is indeed very closely guarded by the cell as its higher levels are cytotoxic for the organism. The dynamic responsiveness of MG-metabolizing GLY pathway to both endogenous cues such as, phytohormones, nutrient status, etc., as well as external environmental fluctuations (abiotic and biotic stresses) indicates that a tight regulation occurs in the cell to maintain physiological levels of MG in the system. Interestingly, GLY pathway is also manipulated by its substrates and reaction products. Hence, an investigation of signalling and regulatory aspects of GLY pathway would be worthwhile. Herein, we have attempted to converge all known factors acting as signals or directly regulating GLYI/II enzymes in plants. Further, we also discuss how crosstalk between these different signal molecules might facilitate the regulation of glyoxalase pathway. We believe that MG detoxification is controlled by intricate mechanisms involving a plethora of signal molecules.