Open AccessMapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development
Author(s) -
Hao Lei,
Lei Li,
Menglu Chen,
Jiahua Xu,
Min Jiang,
Yanpei Wang,
Linhua Jiang,
Xu Chen,
Jiang Qiu,
Shuping Tan,
JiaHong Gao,
Yong He,
Sha Tao,
Qi Dong,
Shaozheng Qin
Publication year - 2021
Publication title -
neuroscience bulletin/neuroscience bulletin
Language(s) - English
Resource type - Journals
eISSN - 1673-7067
pISSN - 1995-8218
DOI - 10.1007/s12264-021-00650-7
Subject(s) - neuroimaging , cognition , functional magnetic resonance imaging , brain activity and meditation , functional neuroimaging , psychology , set (abstract data type) , workflow , brain mapping , toolbox , cognitive psychology , computer science , neuroscience , electroencephalography , database , programming language
The human brain undergoes rapid development during childhood, with significant improvement in a wide spectrum of cognitive and affective functions. Mapping domain- and age-specific brain activity patterns has important implications for characterizing the development of children's cognitive and affective functions. The current mainstay of brain templates is primarily derived from structural magnetic resonance imaging (MRI), and thus is not ideal for mapping children's cognitive and affective brain development. By integrating task-dependent functional MRI data from a large sample of 250 children (aged 7 to 12) across multiple domains and the latest easy-to-use and transparent preprocessing workflow, we here created a set of age-specific brain functional activity maps across four domains: attention, executive function, emotion, and risky decision-making. Moreover, we developed a toolbox named Developmental Brain Functional Activity maps across multiple domains that enables researchers to visualize and download domain- and age-specific brain activity maps for various needs. This toolbox and maps have been released on the Neuroimaging Informatics Tools and Resources Clearinghouse website ( http://www.nitrc.org/projects/dbfa ). Our study provides domain- and age-specific brain activity maps for future developmental neuroimaging studies in both healthy and clinical populations.