Open AccessMouse Pluripotent Stem Cell Differentiation Under Physiological Oxygen Reduces Residual Teratomas
Author(s) -
Jeffrey R. Millman,
Jit Hin Tan,
Clark K. Colton
Publication year - 2021
Publication title -
cellular and molecular bioengineering
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.668
H-Index - 34
eISSN - 1865-5033
pISSN - 1865-5025
DOI - 10.1007/s12195-021-00687-8
Subject(s) - induced pluripotent stem cell , microbiology and biotechnology , biology , cell culture , stem cell , cellular differentiation , partial pressure , oxygen , embryonic stem cell , chemistry , biochemistry , genetics , organic chemistry , gene
Residual pluripotent stem cells (PSC) within differentiated populations are problematic because of their potential to form tumors. Simple methods to reduce their occurrence are needed.