Enhancement of Radio-Thermo-Sensitivity of 5-Iodo-2-Deoxyuridine-Loaded Polymeric-Coated Magnetic Nanoparticles Triggers Apoptosis in U87MG Human Glioblastoma Cancer Cell Line | Zendy

Samideh Khoei | Zendy; Vahid Hosseini | Zendy; Mehdi Hosseini | Zendy; Sepideh Khoee | Zendy; Sakine Shirvalilou | Zendy; Seied Rabi Mahdavi | Zendy; Jalil Pirayesh Islamian | Zendy

Open Access

Enhancement of Radio-Thermo-Sensitivity of 5-Iodo-2-Deoxyuridine-Loaded Polymeric-Coated Magnetic Nanoparticles Triggers Apoptosis in U87MG Human Glioblastoma Cancer Cell Line

Author(s) -

Samideh Khoei,

Vahid Hosseini,

Mehdi Hosseini,

Sepideh Khoee,

Sakine Shirvalilou,

Seied Rabi Mahdavi,

Jalil Pirayesh Islamian

Publication year - 2021

Publication title -

cellular and molecular bioengineering

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.668

H-Index - 34

eISSN - 1865-5033

pISSN - 1865-5025

DOI - 10.1007/s12195-021-00675-y

Subject(s) - hyperthermia , apoptosis , chemistry , cell culture , nanoparticle , polyethylene glycol , mtt assay , prussian blue , peg ratio , magnetic nanoparticles , deoxyuridine , radiosensitivity , biophysics , materials science , nanotechnology , radiation therapy , biochemistry , medicine , biology , surgery , electrode , finance , economics , electrochemistry , genetics , dna

With an emphasis on the radioresistant nature of glioblastoma cells, the aim of the present study was to evaluate the radio-thermo-sensitizing effects of PCL-PEG-coated Superparamagnetic iron oxide nanoparticles (SPIONs) as a carrier of 5-iodo-2-deoxyuridine (IUdR) in monolayer culture of U87MG human glioma cell line.

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