Open AccessEndothelial Cells Morphology in Response to Combined WSS and Biaxial CS: Introduction of Effective Strain Ratio
Author(s) -
Hossein Ali Pakravan,
Mohammad R. Saidi,
Bahar Firoozabadi
Publication year - 2020
Publication title -
cellular and molecular bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.668
H-Index - 34
eISSN - 1865-5033
pISSN - 1865-5025
DOI - 10.1007/s12195-020-00618-z
Subject(s) - materials science , morphology (biology) , population , strain (injury) , perpendicular , biophysics , orientation (vector space) , biomedical engineering , composite material , analytical chemistry (journal) , chemistry , geometry , anatomy , chromatography , mathematics , biology , medicine , genetics , demography , sociology
Endothelial cells (ECs) morphology strongly depends on the imposed mechanical stimuli. These mechanical stimuli include wall shear stress (WSS) and biaxial cyclic stretches (CS). Under combined loading, the effect of CS is not as simple as pure CS. The present study investigates the morphological response of ECs to the realistic mechanical stimuli.