Open AccessUptake of AV-1451 in meningiomas
Author(s) -
Tyler J. Bruinsma,
Derek R. Johnson,
Ping Fang,
Matthew L. Senjem,
Keith A. Josephs,
Jennifer L. Whitwell,
Bradley F. Boeve,
Mukesh K. Pandey,
Kejal Kantarci,
David T. Jones,
Prashanthi Vemuri,
Melissa E. Murray,
Jonathan GraffRadford,
Christopher G. Schwarz,
David S. Knopman,
Ronald C. Petersen,
Clifford R. Jack,
Val J. Lowe
Publication year - 2017
Publication title -
annals of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 58
eISSN - 1864-6433
pISSN - 0914-7187
DOI - 10.1007/s12149-017-1205-0
Subject(s) - medicine , meningioma , nuclear medicine , positron emission tomography , radiology
AV-1451 is an imaging agent labeled with the positron-emitting radiolabel Fluorine-18. 18F-AV-1451 binds paired helical filament tau (PHF-tau), a pathology related to Alzheimer's disease. In our study of AV-1451 uptake in the brains of cognitively normal subjects, we noted a case of a meningioma with visually significant uptake of AV-1451.