Open AccessPolymorphous Adenocarcinoma, Low Grade Variant, Colliding with a Neurofibroma
Author(s) -
Nikolaos Katsoulas,
Konstantinos I. Tosios,
Hannah Afwerke Lynch,
Rachel Uppgaard,
Ioannis G. Koutlas
Publication year - 2021
Publication title -
head and neck pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 50
eISSN - 1936-0568
pISSN - 1936-055X
DOI - 10.1007/s12105-021-01377-7
Subject(s) - medicine , adenocarcinoma , incisional biopsy , asymptomatic , biopsy , soft palate , neurofibroma , pathology , otorhinolaryngology , surgery , cancer , neurofibromatosis
Collision tumors, composed of two distinct benign or malignant neoplasms, are rarely reported in the oral cavity. We present a case of a 61-year-old female with an asymptomatic non-demarcated lump on the soft palate of unknown duration. An incisional biopsy revealed the presence of two neoplastic populations, a neurofibroma that was partially infiltrated by a polymorphous adenocarcinoma, low-grade variant. Total surgical excision was performed, with uneventful follow-up period. The development of collision tumors may be incidental, although molecular events may influence the pathogenetic mechanism of the phenomenon.