Open AccessKaposiform Hemangioendothelioma of the Oral Cavity: A Rare Tumor with an Unusual Location
Author(s) -
Thayná Melo de Lima Morais,
Celeste SánchezRomero,
Luciano Augusto de Araújo Ribeiro,
Daniele Sorgatto Faé,
Francielle Silvestre Verner,
Oslei Paes de Almeida,
Sibele Nascimento de Aquino
Publication year - 2021
Publication title -
head and neck pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 50
eISSN - 1936-0568
pISSN - 1936-055X
DOI - 10.1007/s12105-021-01316-6
Subject(s) - hemangioendothelioma , cd31 , sarcoma , medicine , pathology , cd34 , kasabach–merritt syndrome , head and neck , immunohistochemistry , hemangioma , biology , surgery , stem cell , genetics
Kaposiform hemangioendothelioma is a rare neoplasm with intermediate malignant behavior, mainly affecting infants and children. Involvement head and neck is uncommon, and there are only four cases reported in the oral cavity and oropharynx. Microscopically, it is characterized by a vascular proliferation permeated by spindle-to-ovoid cells resembling Kaposi sarcoma. Immunohistochemically, the tumor is positive for CD31, CD34 and negative for D2-40. Herein we present a rare case of intraoral Kaposiform hemangioendothelioma in a 10-year-old boy.