Open AccessMaxillary Sinus Myxofibrosarcoma Mimicking Nodular Fasciitis: A Rare Case Report
Author(s) -
Bahar Afroozi,
Fatemeh Akbarizadeh,
Amirreza Dehghanian,
Saeid Tavanafar,
Fatemeh Lavaee,
Hossein Danesteh
Publication year - 2021
Publication title -
head and neck pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 50
eISSN - 1936-0568
pISSN - 1936-055X
DOI - 10.1007/s12105-021-01298-5
Subject(s) - nodular fasciitis , medicine , myxofibrosarcoma , malignancy , histopathology , pathology , soft tissue , sarcoma , biopsy , dermatopathology , soft tissue sarcoma , oral and maxillofacial surgery , lesion , surgery
Myxofibrosarcoma (MFS) is a fibroblastic soft tissue sarcoma that is extremely rare in the maxillofacial region. Due to its non-specific clinicoradiographic findings and challenging histopathological features, the diagnosis is difficult. Here, we present a case of MFS which was first diagnosed as nodular fasciitis. The initial examination of the incisional biopsy showed a benign-appearing proliferation of fibroblasts without features of malignancy. The patient returned with recurrence four months after surgical excision of the primary lesion. The second histologic study revealed a high-grade spindle cell sarcoma with myxoid features most compatible with MFS. Definitive diagnosis of MFS was confirmed by these histopathologic features and supportive immunohistochemical stains. Unfortunately, the patient died of disease 3 months later.