Synchronous Multifocal Canalicular Adenomas | Zendy

Ahmed S. Sultan | Zendy; Frank Chang | Zendy; Thomas J. Cooper | Zendy; Maryam Jessri | Zendy

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Synchronous Multifocal Canalicular Adenomas

Author(s) -

Ahmed S. Sultan,

Frank Chang,

Thomas J. Cooper,

Maryam Jessri

Publication year - 2021

Publication title -

head and neck pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.801

H-Index - 50

eISSN - 1936-0568

pISSN - 1936-055X

DOI - 10.1007/s12105-021-01293-w

Subject(s) - pathology , buccal mucosa , stroma , immunohistochemistry , adenoma , medicine , anatomy , biology , oral cavity , orthodontics

Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

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