Open AccessA review of non‐prostanoid, eicosanoid receptors: expression, characterization, regulation, and mechanism of action
Author(s) -
Biringer Roger G.
Publication year - 2022
Publication title -
journal of cell communication and signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 44
eISSN - 1873-961X
pISSN - 1873-9601
DOI - 10.1007/s12079-021-00630-6
Subject(s) - eicosanoid , prostanoid , receptor , eicosanoid metabolism , inflammation , microbiology and biotechnology , signal transduction , homeostasis , g protein coupled receptor , mechanism (biology) , biology , immunology , biochemistry , enzyme , philosophy , epistemology , arachidonic acid
Eicosanoid signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain and to cell survival itself. Disruption of normal eicosanoid signaling is implicated in numerous disease states. Eicosanoid signaling is facilitated by G‐protein‐coupled, eicosanoid‐specific receptors and the array of associated G‐proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of non‐prostanoid, eicosanoid receptors.