Open AccessThymoma associated with pure red cell aplasia: a case report and literature review
Author(s) -
Reenus Demel Xavier,
Sujith Devaraj,
Vijay Sekharappa,
Om Prakasam,
Narendra Me,
Ashok Hariharan,
Thiagarajamurthy Sundaramoorthi
Publication year - 2020
Publication title -
indian journal of thoracic and cardiovascular surgery/indian journal of thoracic and cardiovascular surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.114
H-Index - 9
eISSN - 0973-7723
pISSN - 0970-9134
DOI - 10.1007/s12055-019-00875-2
Subject(s) - thymoma , thymectomy , pure red cell aplasia , medicine , immunosuppression , regimen , surgery , complication , aplasia , cardiothoracic surgery , myasthenia gravis , anemia
Pure red cell aplasia (PRCA) is a rare hematological complication associated with thymoma. Remission of PRCA occurs after thymectomy but can reappear after a latency period even without recurrence of thymoma. We report a case and we have reviewed the literature of thymoma associated with PRCA. Because of less number of reported cases, there have been no clinical trials investigating the immunosuppression regimen following thymectomy for thymoma associated with PRCA. After reviewing the literature, we came to a conclusion that thymectomy followed by immumosuppression with the cyclosporin-containing regimen is currently the most effective treatment.