Open AccessSpreading Depolarization After Chronic Subdural Hematoma Evacuation: Associated Clinical Risk Factors and Influence on Clinical Outcome
Author(s) -
Christine Meadows,
Herbert Davis,
Laila Mohammad,
C. William Shuttleworth,
Michel T. Torbey,
Yiliang Zhu,
Ali A. Alsarah,
Andrew P. Carlson
Publication year - 2021
Publication title -
neurocritical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 74
eISSN - 1556-0961
pISSN - 1541-6933
DOI - 10.1007/s12028-021-01339-5
Subject(s) - medicine , glasgow coma scale , glasgow outcome scale , odds ratio , confidence interval , cohort , retrospective cohort study , neurology , etiology , cohort study , population , pediatrics , surgery , psychiatry , environmental health
Chronic subdural hematoma (cSDH) is a common neurosurgical condition responsible for excess morbidity, particularly in the geriatric population. Recovery after evacuation is complicated by fluctuating neurological deficits in a high proportion of patients. We previously demonstrated that spreading depolarizations (SDs) may be responsible for some of these events. In this study, we aim to determine candidate risk factors for probable SD and assess the influence of probable SD on outcome.