Open AccessHyperoxemia and Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage
Author(s) -
Rebecca A. Reynolds,
Shaunak N Amin,
Sumeeth Jonathan,
Alan R. Tang,
Matthews Lan,
Chunxue Wang,
Julie A. Bastarache,
Lorraine B. Ware,
Reid C. Thompson
Publication year - 2020
Publication title -
neurocritical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 74
eISSN - 1556-0961
pISSN - 1541-6933
DOI - 10.1007/s12028-020-01136-6
Subject(s) - medicine , subarachnoid hemorrhage , vasospasm , cerebral vasospasm , modified rankin scale , aneurysm , asymptomatic , cohort , anesthesia , retrospective cohort study , glasgow outcome scale , ischemia , cardiology , surgery , glasgow coma scale , ischemic stroke
Cerebral vasospasm is a major contributor to disability and mortality after aneurysmal subarachnoid hemorrhage. Oxidation of cell-free hemoglobin plays an integral role in neuroinflammation and is a suggested source of tissue injury after aneurysm rupture. This study sought to determine whether patients with subarachnoid hemorrhage and cerebral vasospasm were more likely to have been exposed to early hyperoxemia than those without vasospasm.