Open AccessMean Arterial Pressure and Discharge Outcomes in Severe Pediatric Traumatic Brain Injury
Author(s) -
Scott Erickson,
Elizabeth Y Killien,
Mark S. Wainwright,
Brianna Mills,
Monica S. Vavilala
Publication year - 2020
Publication title -
neurocritical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 74
eISSN - 1556-0961
pISSN - 1541-6933
DOI - 10.1007/s12028-020-01121-z
Subject(s) - medicine , glasgow coma scale , percentile , mean arterial pressure , traumatic brain injury , blood pressure , glasgow outcome scale , poisson regression , cerebral perfusion pressure , intracranial pressure , anesthesia , cerebral blood flow , heart rate , population , statistics , mathematics , environmental health , psychiatry
Optimizing blood pressure is an important target for intervention following pediatric traumatic brain injury (TBI). The existing literature has examined the association between systolic blood pressure (SBP) and outcomes. Mean arterial pressure (MAP) is a better measure of organ perfusion than SBP and is used to determine cerebral perfusion pressure but has not been previously examined in relation to outcomes after pediatric TBI. We aimed to evaluate the strength of association between MAP-based hypotension early after hospital admission and discharge outcome and to contrast the relative strength of association of hypotension with outcome between MAP-based and SBP-based blood pressure percentiles.