Open AccessLiver Fibrosis and Perihematomal Edema Growth in Primary Intracerebral Hemorrhage
Author(s) -
Neal S Parikh,
Arun Jesudian,
Hooman Kamel,
Daniel F. Hanley,
Wendy Ziai,
Santosh B. Murthy
Publication year - 2020
Publication title -
neurocritical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 74
eISSN - 1556-0961
pISSN - 1541-6933
DOI - 10.1007/s12028-020-01081-4
Subject(s) - medicine , intracerebral hemorrhage , fibrosis , gastroenterology , retrospective cohort study , clinical endpoint , cohort , stroke (engine) , clinical trial , subarachnoid hemorrhage , mechanical engineering , engineering
Liver disease is associated with altered serum osmolality, increased thrombin generation, and systemic inflammation, all of which may contribute to perihematomal edema (PHE) after intracerebral hemorrhage (ICH). We evaluated the association between a validated liver fibrosis index and PHE growth in a cohort of patients with primary ICH.