Open AccessRAR-Related Orphan Receptor Gamma T (RoRγt)-Related Cytokines Play a Role in Neutrophil Infiltration of the Central Nervous System After Subarachnoid Hemorrhage
Author(s) -
Aminata P. Coulibaly,
William Gartman,
Valerie Swank,
João Gomes,
L Ruozhuo,
J DeBacker,
J. Javier Provencio
Publication year - 2019
Publication title -
neurocritical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 74
eISSN - 1556-0961
pISSN - 1541-6933
DOI - 10.1007/s12028-019-00871-9
Subject(s) - medicine , subarachnoid hemorrhage , central nervous system , meninges , cerebrospinal fluid , neurology , immunology , pathology , psychiatry
How inflammatory cells are recruited into the central nervous system is a topic of interest in a number of neurological injuries. In aneurysmal subarachnoid hemorrhage (SAH), neutrophil accumulation in the central nervous system 3 days after the hemorrhage is a critical step in the development of delayed cerebral injury (DCI). The mechanism by which neutrophils enter the central nervous system is still unclear.