Open AccessUltrasound characterization for thyroid nodules with indeterminate cytology: inter-observer agreement and impact of combining pattern-based and scoring-based classifications in risk stratification
Author(s) -
Cesar Lam,
Melissa McGettigan,
Zachary Thompson,
Laila Khazai,
Christine H. Chung,
Barbara A. Centeno,
Bryan McIver,
Pablo Valderrábano
Publication year - 2019
Publication title -
endocrine
Language(s) - English
Resource type - Journals
eISSN - 1559-0100
pISSN - 1355-008X
DOI - 10.1007/s12020-019-02000-0
Subject(s) - thyroid nodules , echogenicity , indeterminate , medicine , radiology , ultrasound , risk stratification , malignancy , pathology , mathematics , pure mathematics
The American Thyroid Association (ATA) sonographic patterns stratify the risk of malignancy of cytologically indeterminate thyroid nodules (ITNs). This study aimed to (1) assess inter-observer agreement for sonographic features and patterns; (2) identify potential sources of disagreement; and (3) evaluate whether the number of suspicious features risk-stratifies non-ATA and high-suspicion patterns.