Open AccessNovel high molecular weight albumin-conjugated angiotensin II activates β-arrestin and G-protein pathways
Author(s) -
Hong Weng Pang,
Andrea Linares,
Leena Couling,
Jessica Santollo,
Leonardo R. Ancheta,
Derek Daniels,
Robert C. Speth
Publication year - 2019
Publication title -
endocrine
Language(s) - English
Resource type - Journals
eISSN - 1559-0100
pISSN - 1355-008X
DOI - 10.1007/s12020-019-01930-z
Subject(s) - angiotensin ii , angiotensin ii receptor type 1 , endocrinology , medicine , chemistry , receptor , aldosterone , bovine serum albumin , angiotensin receptor , biology , biochemistry
To study the ability of a novel bovine serum albumin-angiotensin II (BSA-Ang II) conjugate to effect responses of the AT 1 angiotensin II receptor subtype mediated by the G-protein-coupled and the beta-arrestin pathways.