Phenotypic and Functional Characterization of Mesenchymal Stem Cells from Chorionic Villi of Human Term Placenta | Zendy

Mohamed Abumaree | Zendy; Mohammed Al Jumah | Zendy; Bill Kalionis | Zendy; Dunia Jawdat | Zendy; Abdulaziz Al Khaldi | Zendy; A. A. AlTalabani | Zendy; B. A. Knawy | Zendy

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Phenotypic and Functional Characterization of Mesenchymal Stem Cells from Chorionic Villi of Human Term Placenta

Author(s) -

Mohamed Abumaree,

Mohammed Al Jumah,

Bill Kalionis,

Dunia Jawdat,

Abdulaziz Al Khaldi,

A. A. AlTalabani,

B. A. Knawy

Publication year - 2012

Publication title -

stem cell reviews and reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.247

H-Index - 73

eISSN - 2629-3269

pISSN - 2629-3277

DOI - 10.1007/s12015-012-9385-4

Subject(s) - mesenchymal stem cell , biology , stem cell , cd44 , cd146 , microbiology and biotechnology , immunology , stromal cell , cancer research , cd34 , cell , genetics

Bone marrow derived mesenchymal stem cells (BM-MSCs) are used extensively in transplantation but their use is associated with many problems including low abundance in BM, low overall number, decreased differentiation potential with age and the invasive isolation procedures needed to obtain BM. We report a novel method of isolating placental MSCs (pMSCs) from chorionic villi, which exhibit the phenotypic and functional characteristics that will make them an attractive source of MSCs for cell-based therapy.

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