Open AccessIntraoperative Extracorporeal Irradiation and Frozen Treatment on Tumor-bearing Autografts Show Equivalent Outcomes for Biologic Reconstruction
Author(s) -
Po Kuei Wu,
Cheng-Fong Chen,
Yu Cheng,
Shi-Chun Tsai,
Tain Hsiung Chen,
Wei Ming Chen
Publication year - 2018
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1007/s11999.0000000000000022
Subject(s) - medicine , extracorporeal , surgery , orthopedic surgery
Immediately recycling the resected bone segment in a biologic limb salvage reconstruction is an option after wide resection of bone. Intraoperative extracorporeal irradiation and freezing are the two major tumor-killing techniques applied on the fresh tumor-bearing autografts. However, graft-derived tumor recurrence and complications are concerns affecting graft survival.