Open AccessIs Vancomycin-only Prophylaxis for Patients With Penicillin Allergy Associated With Increased Risk of Infection After Arthroplasty?
Author(s) -
Timothy L. Tan,
Bryan D. Springer,
John A. Ruder,
Michael R. Ruffolo,
Antonia F. Chen
Publication year - 2016
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1007/s11999-015-4672-4
Subject(s) - medicine , vancomycin , penicillin , penicillin allergy , antibiotic prophylaxis , allergy , arthroplasty , orthopedic surgery , infection risk , antibiotics , intensive care medicine , surgery , immunology , microbiology and biotechnology , staphylococcus aureus , biology , bacteria , genetics
Preoperative antibiotic prophylaxis remains one of the most important strategies for prevention of postoperative infection. In patients with penicillin allergy, alternative medications such as vancomycin are often used despite reduced antimicrobial coverage and recent literature questioning the efficacy of vancomycin monotherapy.