Open AccessEnergy Metabolism of Osteocytes
Author(s) -
Vivin Karthik,
Anyonya R. Guntur
Publication year - 2021
Publication title -
current osteoporosis reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.472
H-Index - 57
eISSN - 1544-2241
pISSN - 1544-1873
DOI - 10.1007/s11914-021-00688-6
Subject(s) - osteocyte , bioenergetics , bone remodeling , microbiology and biotechnology , osteoblast , bone resorption , anabolism , bone cell , biology , chemistry , mitochondrion , endocrinology , biochemistry , in vitro
In this review, we provide a recent update on bioenergetic pathways in osteocytes and identify potential future areas of research interest. Studies have identified a role for regulation of bone formation and bone resorption through osteocyte mechanosensing and osteocyte secreted factors. Nevertheless, there is a paucity of studies on the bioenergetics and energy metabolism of osteocytes, which are required for the regulation of bone remodeling.