Open AccessTranscriptomics: a Solution for Renal Osteodystrophy?
Author(s) -
Aline Martin,
Véronique David
Publication year - 2020
Publication title -
current osteoporosis reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.472
H-Index - 57
eISSN - 1544-2241
pISSN - 1544-1873
DOI - 10.1007/s11914-020-00583-6
Subject(s) - renal osteodystrophy , pathogenesis , transcriptome , kidney disease , bioinformatics , disease , medicine , osteodystrophy , bone disease , chronic kidney disease mineral and bone disorder , osteoporosis , pathology , biology , gene expression , gene , genetics
The molecular mechanisms of the bone disease associated with chronic kidney disease (CKD), called renal osteodystrophy (ROD), are poorly understood. New transcriptomics technologies may provide clinically relevant insights into the pathogenesis of ROD. This review summarizes current progress and limitations in the study and treatment of ROD, and in transcriptomics analyses of skeletal tissues.