Open AccessEffects of Diabetes on Bone Material Properties
Author(s) -
Sashank Lekkala,
Erik A. Taylor,
Heather B. Hunt,
Eve Donnelly
Publication year - 2019
Publication title -
current osteoporosis reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.472
H-Index - 57
eISSN - 1544-2241
pISSN - 1544-1873
DOI - 10.1007/s11914-019-00538-6
Subject(s) - medicine , cancellous bone , bone mineral , diabetes mellitus , endocrinology , pentosidine , type 1 diabetes , osteoporosis , bone remodeling , type 2 diabetes mellitus , nonunion , glycation , surgery
Individuals with type 1 and type 2 diabetes mellitus (T1DM, T2DM) have an increased risk of bone fracture compared to non-diabetic controls that is not explained by differences in BMD, BMI, or falls. Thus, bone tissue fracture resistance may be reduced in individuals with DM. The purpose of this review is to summarize work that analyzes the effects of T1DM and T2DM on bone tissue compositional and mechanical properties.