Open AccessMoving the Dial Toward Equity in Parkinson’s Disease Clinical Research: a Review of Current Literature and Future Directions in Diversifying PD Clinical Trial Participation
Author(s) -
Jennifer Adrissi,
Jori Fleisher
Publication year - 2022
Publication title -
current neurology and neuroscience reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.756
H-Index - 72
eISSN - 1534-6293
pISSN - 1528-4042
DOI - 10.1007/s11910-022-01212-8
Subject(s) - generalizability theory , clinical trial , psychological intervention , clinical research , medicine , health equity , equity (law) , disease , ethnic group , public relations , psychology , political science , pathology , nursing , developmental psychology , law , public health
Parkinson's disease (PD), the second most common neurodegenerative disease, has a worldwide prevalence projected at 12 million by 2040. While PD has been extensively researched, our understanding of the disease is based on research studies that include mostly participants of European descent. The lack of diversity in clinical trial enrollment has limited the generalizability of scientific discoveries in the field. Here, we discuss contributors to racial and ethnic disparities in PD clinical research enrollment, summarize recently proposed and tested interventions, and propose next steps to increase equity and representation in PD research.