Open AccessInflammation, Lymphatics, and Cardiovascular Disease: Amplification by Chronic Kidney Disease
Author(s) -
Valentina Kon,
Elaine L. Shelton,
Ashley Pitzer,
Haichun Yang,
Annet Kirabo
Publication year - 2022
Publication title -
current hypertension reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.434
H-Index - 75
eISSN - 1534-3111
pISSN - 1522-6417
DOI - 10.1007/s11906-022-01206-4
Subject(s) - lymphatic system , lymphangiogenesis , medicine , kidney , kidney disease , pathology , nephrology , lymph , inflammation , immunology , cancer , metastasis
Kidney disease is a strong modulator of the composition and metabolism of the intestinal microbiome that produces toxins and inflammatory factors. The primary pathways for these harmful factors are blood vessels and nerves. Although lymphatic vessels are responsible for clearance of interstitial fluids, macromolecules, and cells, little is known about whether and how kidney injury impacts the intestinal lymphatic network.