Open AccessHIV Pathogenesis in the Human Female Reproductive Tract
Author(s) -
Marta Rodríguez-García,
Kaleigh A. Connors,
Mimi Ghosh
Publication year - 2021
Publication title -
current hiv/aids reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.135
H-Index - 56
eISSN - 1548-3576
pISSN - 1548-3568
DOI - 10.1007/s11904-021-00546-1
Subject(s) - immunology , human immunodeficiency virus (hiv) , immune system , medicine , pandemic , pathogenesis , transmission (telecommunications) , serostatus , psychological intervention , disease , viral load , infectious disease (medical specialty) , covid-19 , psychiatry , electrical engineering , engineering
Women remain disproportionately affected by the HIV/AIDS pandemic. The primary mechanism for HIV acquisition in women is sexual transmission, yet the immunobiological factors that contribute to HIV susceptibility remain poorly characterized. Here, we review current knowledge on HIV pathogenesis in women, focusing on infection and immune responses in the female reproductive tract (FRT).