Open AccessEditing of Endogenous Genes in Cellular Immunotherapies
Author(s) -
Theodore L. Roth
Publication year - 2020
Publication title -
current hematologic malignancy reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.299
H-Index - 35
eISSN - 1558-822X
pISSN - 1558-8211
DOI - 10.1007/s11899-020-00587-0
Subject(s) - genome editing , crispr , electroporation , computational biology , endogeny , gene , biology , immunotherapy , genetic enhancement , gene knockin , genetics , cancer , endocrinology
T cell-based cellular and antibody immunotherapies have dramatically altered the landscape of cancer treatment over the past decade. Over the same time span, gene editing technologies have enabled unprecedented degrees of genetic control.