Open AccessAdvances in the Diagnosis and Treatment of Large Granular Lymphocytic Leukemia
Author(s) -
HeeJin Cheon,
Karolina Dziewulska,
Katharine B. Moosic,
Kristine C. Olson,
Alejandro A. Gru,
David J. Feith
Publication year - 2020
Publication title -
current hematologic malignancy reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.299
H-Index - 35
eISSN - 1558-822X
pISSN - 1558-8211
DOI - 10.1007/s11899-020-00565-6
Subject(s) - leukemia , medicine , pathogenesis , immunology , clinical trial , acute leukemia , hematology , bone marrow , population , bioinformatics , oncology , biology , environmental health
The past decade in LGL leukemia research has seen increased pairing of clinical data with molecular markers, shedding new insights on LGL leukemia pathogenesis and heterogeneity. This review summarizes the current standard of care of LGL leukemia, updates from clinical trials, and our congruent improved understanding of LGL pathogenesis.