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Electrospray mass spectrometry for characterizing polyglycerols and the effects of adduct ion and cone voltage
Author(s) -
Crowther Molly W.,
O’Connell Terrence R.,
Carter Stephen P.
Publication year - 1998
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/s11746-998-0343-x
Subject(s) - chemistry , mass spectrometry , dispersity , electrospray , adduct , electrospray ionization , molar mass distribution , analytical chemistry (journal) , ion , chromatography , polymer chemistry , organic chemistry , polymer
Polyglycerol intermediates have been characterized by liquid chromatography‐mass spectrometry (LC‐MS) with electrospray ionization (ESI). Linear and cyclic components from n =2–23 in a sample of decaglycerol, for example, have been resolved in the second dimension or mass axis. Molecular weight (MW) distributions for tri‐, hexa‐, and decaglycerol products have been analyzed as a function of cone voltage and adduct ion (H + , Li + , Na + , K + , Rb + , Cs + , and NH 4 + ). A different combination is required to obtain a reliable MW distribution for each polyglycerol intermediate. The best distribution obtained by ESI/MS is determined by comparing the calculated hydroxyl number and cyclic content to that obtained by wet chemistry and gas chromatography, respectively. Once ESI/MS conditions are established, the distribution can be used, for the first time in polyglycerol analysis, to calculate important parameters such as number average MW, weight average MW, polydispersity, % cyclics, hydroxyl number, wt% above n =6, etc.