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A preliminary study on platelet aggregation in postmenopausal women consuming extra‐virgin olive oil and high‐oleic acid sunflower oil
Author(s) -
SánchezMuniz F. J.,
Oubiña P.,
Benedí J.,
Ródenas S.,
Cuesta C.
Publication year - 1998
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/s11746-998-0034-7
Subject(s) - sunflower oil , food science , oleic acid , chemistry , polyunsaturated fatty acid , linoleic acid , olive oil , palmitic acid , fatty acid , platelet aggregation , cholesterol , platelet , biochemistry , medicine
The purpose of the present study was to examine the effects of two monounsaturated fatty acid‐rich oils, extravirgin olive oil (EVOO) and high‐oleic sunflower oil (HOSO), on platelet aggregation in 14 postmenopausal women (aged 62.9 ± 1.8 yr) with high‐fat dietary habits. Both oils contained oleic acid as the major compound (≈76% of total fatty acids), but the content of palmitic and linoleic acids and many minor compounds was significantly different. These oils were used as the only culinary fats during two 28‐d periods, and represented ≈62% of the total lipid intake (≈46% of total energy consumption). Other dietary components were matched. The daily energy contribution of saturated, monounsaturated, and polyunsaturated fatty acids to the total energy consumption was 11.8, 28.5, and 2.8%, respectively, during the EVOO dietary period and 10.3, 27.8, and 4.6%, respectively, with HOSO. Aggregation in platelet‐rich plasma was measured after addition of ADP. Platelet aggregation (expressed as cm/5 min) was significantly lower after the EVOO diet than after HOSO (2.1 ± 1.1 and 3.0 ± 1.4, respectively; P <0.05). Although maximal aggregation time was 40.2% higher in HOSO than in EVOO, the difference was not significant. Independent of serum cholesterol level, platelet aggregation tended to be different on the EVOO diet when women were classified according to cholesterol levels: <220 mg/dL or ≥220 mg/dL. Results suggest that other compounds present in the oils aside from the fatty acids may play an important role in modulating platelet aggregation in these postmenopausal women.