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Antioxidation Behavior of Milkweed Oil 4‐Hydroxy‐3‐methoxycinnamate Esters in Phospholipid Bilayers
Author(s) -
Evans Kervin O.,
HarryO'kuru Rogers E.
Publication year - 2013
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/s11746-013-2323-z
Subject(s) - ferulic acid , phospholipid , chemistry , lipid peroxidation , polyunsaturated fatty acid , vesicle , moiety , micelle , organic chemistry , antioxidant , chromatography , biochemistry , fatty acid , membrane , aqueous solution
Milkweed ( Asclepia syriaca ) has seed oil that is rich in polyunsaturated triacylglycerides that contain olefinic groups. The olefinic groups can be chemically oxidized to form either epoxy or polyhydroxy triacylglycerides that can be esterified with trans ‐4‐hydroxy‐3‐methoxycinnamic acid, commonly known as ferulic acid. Thin layer chromatography experiments demonstrated that these novel lipids incorporated well into phospholipid vesicles, did not form independent micelles, and their incorporation was not limited by the attached ferulic moiety. Leakage experiments showed that both epoxy derived and polyhydroxy ferulated triacylglycerides reduced leakage of vesicles. Lipid peroxidation measurements demonstrated that both epoxy derived and polyhydroxy forms of ferulated milkweed oil are capable of preventing lipid peroxidation with the polyhydroxy form having the greater capability.