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Bactericidal and Antioxidant Activity of Essential Oils from Myristica fragrans Houtt and Salvia microphylla H.B.K
Author(s) -
Lima Rafaela K.,
Cardoso Maria das Graças,
Andrade Milene A.,
Guimarães Paula L.,
Batista Luís R.,
Nelson David L.
Publication year - 2012
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/s11746-011-1938-1
Subject(s) - myristica fragrans , essential oil , sabinene , chemistry , dpph , nutmeg , food science , linoleic acid , antioxidant , traditional medicine , chromatography , botany , biology , biochemistry , limonene , fatty acid , medicine
This study chemically characterizes and evaluates the bactericidal and antioxidant activities of essential oils from Myristica fragrans and Salvia microphylla . The essential oils were obtained by steam distillation and were subsequently subjected to analysis by GC–MS and GC. The agar diffusion test was employed to evaluate the bactericidal activity, while the 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) and β‐carotene/linoleic acid tests were used to determine the antioxidant activity. Terpin‐4‐ol (14.95%), sabinene (13.07%) and γ‐terpinene (11.22%) were found to be the major constituents in the essential oil of M. fragrans by gas chromatography, whereas ( E )‐caryophyllene (15.35%), α‐eudesmol (14.06%), β‐eudesmol (8.74%) and γ‐eudesmol (7.64%) were encountered in the essential oil of S. microphylla . Both essential oils showed bactericidal activity, with the essential oil of S. microphylla being more efficient. The antioxidant activity of the essential oils from M. fragrans and S. microphylla were demonstrated by the β‐carotene/linoleic acid test, with IC 50 976 and IC 50 770 μg/mL, respectively.