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Synthesis, Characterization and Free Radical Scavenging Properties of Rosmarinic Acid Fatty Esters
Author(s) -
Lecomte Jérôme,
Giraldo Luis Javier López,
Laguerre Mickaël,
Baréa Bruno,
Villeneuve Pierre
Publication year - 2010
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/s11746-010-1543-8
Subject(s) - rosmarinic acid , chemistry , methanol , scavenging , alkyl , fatty acid , organic chemistry , sulfonic acid , primary (astronomy) , catalysis , chromatography , antioxidant , physics , astronomy
The hydrophobation of rosmarinic acid with saturated aliphatic primary alcohols of various chain lengths (methanol to eicosanol) was achieved via an acid‐catalyzed esterification in the presence of a highly acidic sulfonic resin. The resulting alkyl rosmarinates were isolated, characterized and their global free radical scavenging activity was determined by the 2,2‐diphenyl‐1‐picrylhydrazyl method in the stationary state. Only the dodecyl ester showed a stronger activity than rosmarinic acid.